Kyle founded PatientCrossroads in 2004. Kyle is a respected authority on rare disease patient registries and is a frequent speaker at research conferences educating the non-profit and research community on the need for universally accessible, de-identified patient information. Kyle's passion is to change the economics of patient provided information from closed, proprietary access, to universally available self-funding programs that accelerate disease research.

Prior to PatientCrossroads, Kyle was a consultant to several pharmaceutical companies helping to streamline translational research programs through information technology. Kyle was the founder of Ignite Knowledge Management one of the first SaaS (Software as a Service) business now owned by British Telecom. He has a BS in Business Operations and Systems Management from Indiana University and has advised to the Life Sciences Information Technology Global Institute and One-Mind for Research.